Scientific Research Papers

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Over 150 refereed journal articles, application notes & white papers using DRS Daylight Solutions’ QCL-based technologies

Over the past few years, quantum cascade lasers (QCL) have evolved from scientific curiosities to enablers of commercial instruments, providing sensing, detection, and molecular spectroscopy. Here you’ll find discussions ranging from the basic physics of QCL core technology to system level applications. Topics include stand-off explosive detection, distributed sensor networks, trace gas analysis, ring resonators and waveguides, as well as in vitro glucose detection, and mid-IR imaging. Feel free to review and download information of interest from this growing pool of resources.

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Scientific Research Paper Title
Imaging-based molecular barcoding with pixelated dielectric metasurfacesAndreas Tittl, Aleksandrs Leitis, Mingkai Liu, Filiz Yesilkoy, Duk-Yong Choi, Dragomir N. Neshev, Yuri S. Kivshar, Hatice Altug Science/DOI: 10.1126/science.aas9768Chemical Imaging, Biomedical, Material Analysis, Environmental MonitoringSpero, Spero-QT2018
Quantum Cascade Laser-Based Infrared Microscopy for Label-Free and Automated Cancer Classifcation in Tissue SectionsClaus Kuepper, Angela Kallenbach-Thieltges, Hendrik Juette, Andrea Tannapfel, Frederik Großerueschkamp, Klaus Gerwert Scientific Reports/ DOI:10.1038/s41598-018-26098-wTissue Analysis, Chemical Imaging, Biomedical, Cancer ResearchSpero, Spero-QT2018
A protocol for rapid, label-free histochemical imaging of fibrotic liverB. Bird and J. Rowlette Royal Chemistry Society/ DOI: 10.1039/c6an02080aTissue Analysis, Chemical Imaging, BiomedicalSpero2016
Fourier-transform vs. quantum-cascade-laser infrared microscopes for histo-pathology: From lab to hospital?Abiodun Ogunleke, Vladimir Bobroff, Hsiang-Hsin Chen, Jeremy Rowlette, Maylis Delugin, Benoit Recur, Yeukuang Hwu, Cyril Petibois Analytical Chemistry/ DOI: 10.1016/j.trac.2017.02.007Tissue Analysis, Chemical Imaging, BiomedicalSpero2017
Tests of a two-color interferometer and polarimeter for ITER density measurementsM A Van Zeeland, T N Carlstrom, D K Finkenthal, R L Boivin, A Colio, D Du, A Gattuso, F Glass, C M Muscatello, R O'Neill, M Smiley, J Vasquez, M Watkins, D L Brower, J Chen, W X Ding, D Johnson, P Mauzey, M Perry, C Watts, R Wood Plasma Physics and Controlled Fusion/ DOI: 10.1088/1361-6587/aa8c49PlasmaUnicorn II2017
Nanoscale Mapping and Spectroscopy of Nonradiative Hyperbolic Modes in Hexagonal Boron Nitride NanostructuresLisa V. Brown, Marcelo Davanco, Zhiyuan Sun, Andrey Kretinin, Yiguo Chen, Joseph R. Matson, Igor Vurgaftman, Nicholas Sharac, Alexander J. Giles, Michael M. Fogler, Takashi Taniguchi, Kenji Watanabe, Kostya S. Novoselov, Stefan A. Maier, Andrea Centrone, and Joshua D. Caldwell Nano Letters/ DOI: 10.1021/acs.nanolett.7b04476NanoscaleMIRcat, Hedgehog2018
Absolute spectroscopy near 7.8 μm with a comb-locked extended-cavity quantum-cascade-laserMarco Lamperti, Bidoor AlSaif, Davide Gatti, Martin Fermann, Paolo Laporta, Aamir Farooq, and Marco Marangoni Optical Society of America/ DOI: 10.1364/OL.99.099999Frequency CombsMIRcat, Hedgehog2017
Predicting Fibrosis Progression in Renal Transplant Recipients Using Laser-Based Infrared Spectroscopic ImagingVishal K. Varma, Andre Kajdacsy-Balla, Sanjeev Akkina, Suman Setty, Michael J. Walsh Scientific Reports/ DOI: :10.1038/s41598-017-19006-1Tissue AnalysisSpero2017
The harmonic state of quantum cascade lasers: origin, control, and prospective applicationsMarco Piccardo, Paul Chevalier, Tobias S. Mansuripur, Dmitry Kazakov, Yongrui Wang, Noah A. Rubin, Lauren Meadowcroft, Alexey Belyanin, and Federico Capasso Optics Express/ DOI: 10.1364/OE.26.009464Frequency CombsHedgehog, MIRcat2018
Quantitative Chemical Analysis at the Nanoscale Using the Photothermal Induced Resonance TechniqueGeorg Ramer, Vladimir A. Aksyuk, and Andrea Centrone Analytical Chemistry/ DOI: 10.1021/acs.analchem.7b03878NanoscaleMIRcat2017
High-throughput Quantum Cascade Laser (QCL) spectral histopathology: a practical approach towards clinical translationMichael. J. Pilling, Alex Henderson, Benjamin Bird, Mick D. Brown, Noel W. Clarke, Peter Gardner Royal Chemistry Society/ DOI: 10.1039/C5FD00176ETissue Analysis, Chemical Imaging, BiomedicalSpero2016
High definition infrared chemical imaging of colorectal tissue using a Spero QCL microscopeB. Bird and J. Rowlette Royal Chemistry Society/ DOI: 10.1039/c6an01916aTissue Analysis, Chemical Imaging, BiomedicalSpero2017
Mid-infrared photonic crystal cavities in siliconRaji Shankar, Rick Leijssen, Irfan Bulu, Marko Lončar Optics Express/ Vol. 19, No. 6Sensors, Analyzers & SpectrometersHedgehog, EC-QCL2011
Nanostructured Lipid-Based Films for Substrate-Mediated Applications in BiotechnologyMinjee Kang, Mohit Tuteja, Andrea Centrone, Daniel Topgaard, and Cecilia Leal Advanced Functional Materials/ DOI: 10.1002/adfm.201704356NanoscaleMIRcat2018
Frequency characterization of a swept-and-fixed-wavelength external-cavity quantum cascade laser by use of a frequency combKevin Knabe, Paul A. Williams, Fabrizio R. Giorgetta, Chris M. Armacost, Sam Crivello, Michael B. Radunsky, NathanR. Newbury Optics Express/ Vol. 20, No. 11Frequency CombsEC-QCL, Hedgehog, MIRcat2012
3D Chemical Imaging of the Brain by Quantitative IR Spectro-MicroscopyAbiodun Ogunleke, Benoit Recur, Hugo Balacey, Hsiang-Hsin Chen, Maylis Delugin, Yeukuang Hwu, Sophie Javerzat, Cyril Petibois Royal Society of Chemistry/ DOI: 10.1039/C7SC03306KChemical Imaging, Cancer ResearchSpero2017
Quantum Cascade Laser-Based Measurement of Metal Alkylamide Density During Atomic Layer DepositionJames E. Maslar, William A. Kimes, Brent A. Sperling OSA Vol. 21, No. 10/ DOI: 10.1364/OE.21.011659Sensors, Analyzers & SpectrometersEC-QCL, Hedgehog, MCT Detector2012
Attenuated total reflection mid-IR-spectroscopy for electrochemical applications using a QCLStefanie Pengel, Bernd Schӧnberger, Simantini Nayak, Andreas Erbe Lasers, Sources, and Related Photonic Devices Technical DigestSensors, Analyzers & SpectrometersEC-QCL, Hedgehog, MCT Detector2012
Quantum-Cascade Laser-Based Vibrational Circular DichroismSteffen Lüdeke, Marcel Pfeifer, Peer Fischer Journal of the American Chemical Society/ DOI: 10.1021/ja200539dSensors, Analyzers & SpectrometersEC-QCL, Hedgehog2011
Silicon waveguides and ring resonators at 5.5 µmAlexander Spott, Yang Liu, Tom Baehr-Jones, Rob Ilic, Michael Hochberg Applied Physics Letters 97, 213501Sensors, Analyzers & SpectrometersCW-MHF2010
On-Chip Integrated Mid-Infrared GaAs/AlGaAs Mach-Zehnder InterferometerMarkus Sieger, Franz Balluff, Xiaofeng Wang, Seong-Soo Kim, Lothar Leidner, Guenter Gauglitz, Boris Mizaikoff Analytical Chemistry/ DOI: 10.1021/ac302551sSensors, Analyzers & SpectrometersEC-QCL, Hedgehog, MIRcat2012
3D Quantitative Chemical Imaging of Tissues by SpectromicsCyril Petibois Trends in Biotechnology/ DOI: 10.1016/j.tibtech.2017.08.002Chemical Imaging, Cancer ResearchSpero2017
Development of a tunable polarimetric scatterometry system in the MWIR and LWIRThomas M. Fitzgerald, Michael A Marciniak, Stephen E. Nauyoks Plasma Phys. 52, No. 10/ DOI: 10.1002/ctpp.201200044PlasmaEC-QCL, Hedgehog2010
External cavity widely tunable quantum cascade laser based hollow waveguide gas sensors for multianalyte detectionC. Young, S. S. Kim, Y. Luzinova, M. Weida, D. Arnone, E. Takeuchi, T. Day, B. Mizaikoff Sensors and Acuators B: Chemical/ DOI: 10.1016/j.snb.2009.03.023Sensors, Analyzers, and SpectrometersEC-QCL2009
Applications of Quantum Cascade Lasers in Plasma Diagnostics: A ReviewJ. Rӧpcke, P. B. Davies, N. Lang, A. Rousseau, S. Welzel Journal of Physics D: Applied Physics / DOI: 10.1088/0022-3727/45/42/423001PlasmaEC-QCL2012
Plasma Chemical Study of a RF Discharge Containing Aluminum Tri-Isopropoxide Using MIR Absorption Spectroscopy Based on External-Cavity Quantum Cascade LasersD. Lopatik, S. Niemietz, M. Frӧhlich, J. Rӧpcke, H. Kersten Plasma Phys. 52, No. 10/ DOI: 10.1002/ctpp.201200044PlasmaEC-QCL2012
Morphed intermolecular potential of OC:HCCH complex based on infrared quantum cascade laser spectroscopyLuis A. Rivera-Rivera, Blake A. McElmurry, Zhongcheng Wang, Igor I. Leonov, Robert R. Lucchese, John W. Bevan Chemical Physical Letters/ DOI: 10.1016/j.cplett.2011.11.072Time ResolvedCW/ mode-hop-free, EC-QCL2011
Studying Highly Reactive Organometallic complexes with fast time-resolved infrared spectroscopy using external cavity quantum cascade lasersJames A. Calladine, Michael W. George Spectroscopy Europe Vol. 21, No.6Time ResolvedEC-QCL2009
Application of External-Cavity Quantum Cascade Infrared Lasers to Nanosecond Time-Resolved Infrared Spectroscopy of Condensed-Phase Samples Following Pulse RadiolysisDavid C. Grills, Andrew R. Cook, Etsuko Fujita, Michael W. George, Jack M. Preses, James F. Wishart Applied Spectroscopy Vol. 64, No. 6Time ResolvedEC-QCL, Hedgehog2010
Kinetic and Mechanistic Studies of Carbon-to-Metal Hydrogen Atom Transfer Involving Os-Centered Radicals: Evidence for TunnelingAnna Lewandowska-Andralojk, David C. Grills, Jie Zhang, R. Morris Bullock, Akira Miyazawa, Yuji Kawanishi, Etsuko Fujita Journal of the American Chemical Society/ DOI: 10.1021/ja4123076Time ResolvedCW/ mode-hop-free, EC-QCL2014
Mechanism of the Formation of a Mn-Based CO2 Reduction Catalyst Revealed by Pulse Radiolysis with Time-Resolved Infrared DetectionDavid C. Grills, Jaime A. Farrington, Bobby H. Layne, Jack M. Preses, Sergei V. Lymar, James F. Wishart, Barbara A. Mello Journal of the American Chemical Society/ DOI: 10.1021/ja501051sTime Resolved2014
Radiation Stability of Cations in Ionic Liquids. 5. Task-Specific Ionic Liquids Consisting of Biocompatible Cations and the Puzzle of Radiation HypersensitivityIlya A. Shkrob, Timothy W. Marin, James F. Wishart, David C. Grills The Journal of Physical Chemistry B / DOI: 10.1021/jp5049716Time Resolved2014
Vibrational Stark Effects To Identify Ion Pairing and Determine Reduction Potentials in Electrolyte-Free EnviromentsTomoyasu Mani, David C. Grills, John R. Miller Journal of the American Chemical Society/ DOI: 10.1021/ja512302cTime Resolved2015
Development of nanosecond time-resolved infrared detection at the LEAF pulse radiolysis facilityDavid C. Grills, Jaime A. Farrington, Bobby H. Layne, Jack M. Preses, Herbert J. Bernstein, James F. Wishart Review of Scientific Instruments 86, 044102Time ResolvedEC-QCL, Hedgehog2015
Nanosecond step-scan FTIR spectroscopy of a pulsed external-cavity quantum-cascade laserMarkus Brandstetter, Bernhard Lendl, Andreas Genner Biomedical, Time ResolveEC-QCL
Tunable Mid-Infrared Lasers in Physical Chemosensors towards the Detection of Physiologically Relevant Parameters in BiofluidsMarkus Brandstetter, Bernhard Lendl DOI: 10.1016/j.snb.2011.06.081BiomedicalEC-QCL2011
Infrared and microwave spectra of the acetylene-ammonia and carbonyl sulfide-ammonia complexes: a comparative study of a weak C—H···N Hydrogen bond and an S···N bondXunchen Liu, Yunjie Xu Phys. Chem. Chem. Phys., 2011, 13, 14235-14242BiomedicalMHF2011
Infrared Study of the Folding Mechanism of a Helical Hairpin: Porcine PYYMatthias M. Waegele, Feng Gai Biochemistry/ DOI: 10.1021/bi100851cBiomedical, Protein AnalysisEC-QCL, Hedgehog, MIRcat2010
Real-time mid-IR chemical imaging of dynamic processes: Proton-Dueteron exchange within a micro fluidic system using the Spero™ QCL based microscopeBill Mohar Application Note: 201501Biomedical, Microfluidics, Chemical ImagingSpero2015
Introducing Discrete Frequency Infrared Technology for High-Throughput Biofluid ScreeningCaryn Hughes, Graeme Clemens, Benjamin Bird, Timothy Dawson, Katherine M. Ashton, Michael D. Jenkinson, Andrew Brodbelt, Miles Weida, Edeline Fotheringham, Matthew Barre, Jeremy Rowlette, Matthew J. Baker Scientific Reports/6:20173/ DOI: 10.1038/srep20173Biomedical, Microfluidics, Cancer ResearchSpero2015
Optimization of mid-IR photothermal Imaging for Tissue AnalysisAtcha Totachawattana, Shyamsunder Erramilli, Michelle Y. Sander SPIE Vol. 9584Biomedical, Tissue Analysis, NanoscaleEC-QCL, Hedgehog, Pulsed Tunable Laser2015
Vibrational mid-infrared photothermal spectroscopy using a fiber laser probe: asymptotic limit in signal-to-baseline contrastAtcha Totachawattana, Hui Liu, Alket Mertiri, Mi K. Hong, Shyamsunder Erramilli, Michelle Y. Sander Optics Letters Vol. 41, No. 1BiomedicalEC-QCL, Hedgehog, Pulsed Tunable Laser2016
Effect of Hydrophobic Interactions on the Folding Mechanism of β-HairpinsAlexander Popp, Timothy A. Kiederling, Karin Hauser The Journal of Physical Chemistry B / DOI: 10.1021/jp506658xBiomedical, Protein Analysis, Time ResolveEC-QCL, Hedgehog, Pulsed Tunable Laser2014
Microfluidic cantilever detects bacteria and measures their susceptibility to antibiotics in small confined volumesHashem Etayash, M. F. Khan, Kamaljit Kaur, Thomas Thundat Nature Communications/ DOI: 10.1038/ncomms12947Biomedical, MicrofluidicsMIRcat2016
Application of quantum cascade lasers to trace gas analysisA. Kosterev, G. Wysocki, Y. Bakhirkin, S. So, R. Lewicki, M. Fraser, F. Tittel, R. F. Curl Appl. Phys. B 90, 165-176 DOI: 10.1007/s00340-007-2846-9QCL technology, Gas/Liquid Phase Analysis (SA)EC-QCL, Hedgehog2008
Multi-modal characterization of nanogram amounts of photosensitive polymerSeonghwan Kim, Dongkyu Lee, Minhyuk Yun, Namchul Jung, Sangmin Jeon, Thomas Thundat Applied Physics Letters 102, 024103NanoscaleMIRcat2013
Infrared hyperspectral imaging using a broadly tunable external cavity quantum cascade laser and microbolometer focal plane arrayMark C. Phillips, Nicolas Ho Optics Express 1836, Vol. 16, No. 3Standoff DetectionEC-QCL, Hedgehog2008
Investigation of Standoff Explosives Detection via Photothermal/Photoacoustic InterferometryPak S. Cho, Robert M. Jones, Timothy Shuman, Daniel Scoglietti, Geof Harston Standoff DetectionEC-QCL, Hedgehog, Pulsed Tunable Laser
Quantum cascade laser-based substance detection: approaching the quantum noise limitPeter C. Kuffner, Kathryn J. Conroy, Toby K. Boyson, Greg Milford, Mohamed A. Mabrok, Abhijit G. Kallapur, Ian R. Petersen, Maria E. Calzada, Thomas G. Spence, Kennith P. Kirkbride, Charles C. Harb Standoff DetectionMCT Detector
Ultrasonic photoacoustic spectroscopy of trace hazardous chemicals using quantum cascade laserDeepak Kumar, Devinder Pal Ghai, R.K. Soni Optics Communications Vol. 381, Pages 271-276Standoff Detection2016
Absorption and wavelength modulation spectroscopy of NO2 using a tunable, external cavity continuous wave quantum cascade laserGottipaty N. Rao, Andreas Karpf Applied Optics / Vol. 48, No. 2Environmental MonitoringEC-QCL, Hedgehog2009
High sensitivity detection of NO2 employing cavity ringdown spectroscopy and an external cavity continuously tunable quantum cascade laserGottipaty N. Rao, Andreas Karpf Applied Optics / Vol. 49, No. 26Environmental MonitoringEC-QCL, Hedgehog2010
Mid-IR laser-based sensor for hydrogen peroxide detectionNancy P. Sanchez, Yajun Yu, Lei Dong, Robert J. Griffin, and Frank K. Tittel SPIE Newsroom DOI: 10.1117/2.1201601.006295Environmental MonitoringEC-QCL, Hedgehog2016
Stability of widely tunable, continuous wave external-cavity quantum cascade laser for absorption spectroscopyVasili L. Kasyutich, R.K. Raja Ibrahim, Philip A. Martin Infrared Physics and Technology DOI: 10.1016/j.infrared.2010.07.004QCL technologyEC-QCL, Hedgehog2010
Direct and wavelength modulation spectroscopy using a cw external cavity quantum cascade laserG. Hancock, J. H. van Helden, R. Peverall, G. A. D. Ritchie, and R. J. Walker Applied Physics Letters 94, 201110QCL technologyEC-QCL, Hedgehog2009
Application Note: Continuous tuning of a Daylight Solutions 6.06 µm cw Ecqcl™ without loss of coverage due to mode hops via sequential scans at different laser head temperatures.Gary Douberly QCL technologyCW/ mode-hop-free, EC-QCL2011
Utilizing broad gain bandwidth in quantum cascade devicesMiles J. Weida, David Caffey, Jeremy Rowlette, David F. Arnone, Timothy Day Optical Engineering Vol. 49(11)QCL technologyEC-QCL, Hedgehog2010
A Mid-infrared QEPAS sensor device for TATP detectionBauer, C. et. al. (Tittel) J. Physics: Conference SeriesStandoff Detection2009
Quantum Cascade laser-based Photoacoustic Spectroscopy for Trace Vapor Detection and Molecular DiscriminationEllen Holthoff, Paul Pellegrino, John Bender, Almon Fisher Sensors, ISSN 1424-8220, DOI: 10.3390/s100301986Standoff DetectionEC-QCL, Hedgehog2010
QEPAS detector for rapid spectral measurementsA.A. Kosterev, P.R. Buerki, L. Dong, M. Reed, T. Day, F.K. Tittel Appl Phys B DOI 10.1007/s00340-010-3975-0QCL technology, Gas/Liquid Phase Analysis (SA)EC-QCL, Hedgehog2010
Development of a MEMS-Scale Photoacoustic Chemical Sensor Using a Quantum Cascade LaserEllen L. Holthoff, David A. Heaps, Paul M. Pellegrino IEEE Sensors Journal, Vol. 10, No. 3Standoff DetectionEC-QCL, Hedgehog2010
Performance characteristics of a continuous-wave compact widely tunable external cavity interband cascade lasersDavid Caffey, Timothy Day, Chul Soo Kim, Mijin Kim, Igor Vurgaftman, William W. Bewley, J. Ryan Lindle, Chadwick L. Canedy, Joshua Abell, Jerry R. Meyer Vol. 18, No. 15/ Optics ExpressQCL technologyEC-QCL, Hedgehog2010
NO trace gas sensor based on quartz-enhanced photoacoustic spectroscopy and external cavity quantum cascade laserV. Spagnolo, A.A. Kosterev, L. Dong, R. Lewicki, F.K. Tittel Appl Phys B (2010) 100: 125-130 DOI 10.1007/s00340-010-3984-zQCL technologyEC-QCL, Hedgehog, MHF2010
Distributed nerve gases sensor based on IR absorption in hollow optical fiberR. Viola, N. Liberatore, D. Luciani, S. Mengali, L. Pierno Proc SPIE, Vol 7838, 78380H-1Standoff DetectionEC-QCL, Hedgehog2010
Quantum Cascade lasers in chemical physicsRobert F. Curl, Federico Capasso, Claire Gmachl, Anatoliy A. Kosterev, Barry McManus, Rafal Lewicki, Michael Pusharsky, Gerard Wyscoki, Frank K. Tittel Chemical Physics Letters doi: 10.1016/j.cplett.2009.12.073QCL technology2010
Hollow Core Fiber Optics for Mid-Wave and Long-Wave Infrared SpectorscopyJason M. Kriesel, Nahum Gat, Bruce E. Bernacki, Rebecca L. Erikson, Bret D. Cannon, Tanya L. Myers, Carlos M. Bledt, James A. Harrington SPIE DSS, 8018-31Standoff DetectionEC-QCL, Hedgehog2011
Pump-probe photothermal spectroscopy using quantum cascade lasersR. H. Farahi, A. Passian, L. Tetard, T. Thundat Journal of Physics D: Applied Physics / DOI: 10.1088/0022-3727/45/12/125101Standoff Detection2012
Nanoscale chemical imaging by photoinduced forced microscopyDerek Nowak, William Morrison, H. Kumar Wickramasinghe, Junghoon Jahng, Eric Potma, Lei Wan, Ricardo Ruiz, Thomas R. Albrecht, Kristin Schmidt, Jane Frommer, Daniel P. Sanders, Sung Park Sci. Adv. 2, e1501571Nanoscale2016
Dual beam photoacoustic infrared spectorscopy of solids using an external cavity quantum cascade laserM. Dehghany, K. H. Michaelian Review of Scientific Instruments 83, 064901Standoff DetectionEC-QCL, Hedgehog, MHF2012
Standoff detection of trace explosives via resonant infrared photothermal imagingR. Furstenberg, C. A. Kendziora, J. Stepnowski, S. V. Stepnowski, M. Rake, M. R. Papantonakis, V. Nguyen, G. K. Hubler, R. A. McGill Appl. Phys. Letters 93, 224103Standoff DetectionEC-QCL, Hedgehog, Pulsed Tunable Laser2008
Photoacoustic spectroscopy of surface adsorpbed molecules using a nanstructured coupled resonator arrayDongkyu Lee, Seonghwan Kim, C. W. Van Neste, Moonchan Lee, Sangmin Jeon, Thomas Thundat Nanotechnology/ DOI: 10.1088/0957-4484/25/3/035501Standoff DetectionEC-QCL, Hedgehog2014
Standoff photoacoustic spectroscopyC. W. Van Neste, L. R. Senesac, T. Thundat Applied Physics Letters 92, 234102Standoff DetectionEC-QCL, Hedgehog2008
Risley prism scan-based approach to standoff trace explosive detectionCraig R. Schwarze, Elizabeth Schundler, Robert Vaillancourt, Scott Newbry, Ryan Benedict-Gill Optical Engineering 53(2), 021110Standoff DetectionEC-QCL, Hedgehog2014
Standoff Spectroscopy of Surface Adsorbed ChemicalsC. W. Van Neste, L. R. Senesac, T. Thundat Anal. Chem., 81, 1952-1956Standoff DetectionEC-QCL, Hedgehog2009
Enhanced sensitivity for the detection of trace gases using multiple line integrated absorption spectroscopyAdreas Karpf, Gottipaty N. Rao Applied Optics / Vol. 48, No. 27Environmental MonitoringEC-QCL, Hedgehog, MHF2009
Rapid passage effects in nitrous oxide induced by a chirped external cavity quantum cascade laser,Van Helden, J.H., et. al., (Walker) Appl. Phys. LettEnvironmental Monitoring2009
Heterogeneously Integrated Silicon Photonics for the Mid-Infrared and Spectroscopic SensingYu Chen, Hongtao Lin, Juejun Hu, Mo Li ACS Nano, DOI 10.1021/nn501765kEnvironmental Monitoring, Sensors, Analyzers & SpectrometersEC-QCL, Hedgehog, MIRcat2014
Jet-cooled infrared spectra of molecules and complexes with a cw mode-hop-free external cavity QCL and a distributed-feedback QCLX. Liu, Y. Xu, Z. Su, W.S. Tam, I. Leonov Appl. Phy. B DOI 10.1007/s00340-010-4147-yEnvironmental MonitoringEC-QCL, Hedgehog, MHF2010
Quantum cascade laser open-path system for remote sensing of trace gases in Beijing, ChinaAnna P. M. Michel, Peter Q. Liu, June K. Yeung, Paul Corrigan, Mary Lynn Baeck, Zifa Wang, Timothy Day, Fred Moshary, Claire F. Gmachl Optical Engineering 49(11), 111125Environmental Monitoring, Gas/Liquid Phase Analysis (SA)EC-QCL, Hedgehog2010
Enhancement of trace gas detection by integrating wavelength modulated spectra across multiple linesGottipaty N. Rao, Andreas Karpf Applied Optics / Vol. 49, No. 8Environmental MonitoringEC-QCL, Hedgehog, MHF2010
Extremely sensitive detection of NO2 employing off-axis integrated cavity output spectroscopy coupled with multiple line integrated absorption spectroscopyGottipaty N. Rao, Andreas Karpf Applied Optics / Vol. 50, No. 13Environmental MonitoringEC-QCL, Hedgehog2011
Real-time monitoring of benzene, toluene, and p-xylene in a photoreaction chamber with a tunable mid-infrared laser and ultraviolet differential optical absorption spectroscopyMatthew T. Parsons, Ihor Sydoryk, Alan Lim, Thomas J. McIntyre, John Tulip, Wolfgang Jäger, Karen McDonald Applied Optics / Vol. 50, No. 4Environmental MonitoringEC-QCL, Hedgehog, MHF2011
Chirped quantum cascade laser induced rapid passage signatures in optically thick gasNorthern, J.H., et. al. (Duxbury) Appl. Phys. BEnvironmental Monitoring2011
Ppb-level detection of nitric oxide using an external cavity quantum cascade laser based QEPAS sensorLei Dong, Vincenzo Spangnolo, Rafal Lewicki, Frank K. Tittel Optics Express 24037 / Vol. 19, No.24Environmental MonitoringEC-QCL, Hedgehog2011
Part-per-trillion level SF6 detection using a quartz enhanced photoacoustic spectroscopy-based sensor with single-mode fiber-coupled quantum cascade laser excitationVincenzo Spagnola, Pietro Patimisco, Simone Borri, Gaetano Scamarcio, Bruce E. Bernacki, Jason Kriesel Optics Letters/ Vol. 37, No. 21Environmental MonitoringEC-QCL, Hedgehog, MHF2012
Nonpolar nitrous oxide dimer: Observation of combination bands of (14N2O)2 and (15N2O)2 involving the torsion and antigeared bending modesM. Rezaei, K. H. Michaelian, N. Moazzen-Ahmadi The Journal of Chemical Physics 136, 124308Environmental MonitoringEC-QCL, Hedgehog2012
Real-time monitoring of ozone in air using substrate-integrated hollow waveguide mid-infrared sensorsPetruci, J.F., et. al., (Mizaikoff) Sci. ReportsEnvironmental Monitoring2013
Pulsed quantum cascade laser based hypertemporal real-time headspace measurementsToby K. Boyson, Dylan R. Rittman, Thomas G. Spence, Maria E. Calzada, Abhijit G. Kallapur, Ian R. Petersen, K. Paul Kirkbride, David S. Moore, and Charles C. Harb Optics Express/ Vol. 22, No. 9/ DOI: 10.1364/OE.22.010519Environmental MonitoringEC-QCL, Hedgehog2014
Wavelength-modulation-spectroscopy for real-time, in situ NO detection in combustion gases with a 5.2 µm quantum-cascade laserX. Chao, J.B. Jeffries, R.K. Hanson Appl. Phys. B DOI 10.1007/s00340-011-4839-yEnvironmental MonitoringEC-QCL, Hedgehog2011
Sensitive detection of CO2 concentration and temperature for hot gases using quantum-cascade laser absorption spectroscopy near 4.2 µmKuijun Wu, Faquan Li, Xuewu Cheng, Yong Yang, Xin Lin, Yuan Xia Appl. Phys. B DOI 10.1007/s00340-014-5880-4Environmental MonitoringMHF2014
Multi-band infrared CO2 absorption sensor for sensitive temperature and species measurements in high-temperature gasesR. M. Spearrin, W. Ren, J. B. Jeffries, R. K. Hanson Appl. Phys. B. DOI 10.1007/s00340-014-5772-7Environmental MonitoringEC-QCL, Hedgehog2014
Mid-infrared Absorption Sensor for Measurement of CO and CO2 in Propulsion FlowsR. Mitchell Spearrin, Jay B. Jeffries, Ronald K. Hanson AIAA SciTech 2014-0390Environmental MonitoringEC-QCL, Hedgehog2014
Two-line thermometry and H2O measureent for reactive mixtures in rapid compression machine near 7.6 µmApurba Kumar Das, Mruthunjaya Uddi, Chih-Jen Sung Combustion and Flame 159 (2012) 3493-3501Environmental MonitoringMHF2012
Propene concentration sensing for combustion gases using quantum-cascade laser absorption near 11 µmRobin S. M. Chrystie, Ehson F. Nasir, Aamir Farooq App Phys B DOI 10.1007/s00340-015-6139-4Environmental Monitoring, Gas/Liquid Phase Analysis (SA)EC-QCL, Hedgehog2015
Rovibrational analysis of the water bending vibration I nthe mid-infrared spectrum of atmospherically significant N2-H2O complexS.D. Springer, B.A. McElmurry, Z. Wang, I.I. Leonov, R.R. Lucchese, J.W. Bevan, L.H. Coudert Chemical Physics Letters 633 (2015) 229-233Environmental MonitoringMHF2015
Real-time multiplexed digital cavity-enhanced spectroscopyToby K. Boyson, Paul J. Dagdigian, Karl D. Pavey, Nicholas J. FitzGerald, Thomas G. Spence, David S. Moore, and Charles C. Harb Optics Letters/ Vol. 40, No. 19Environmental MonitoringEC-QCL, Hedgehog2015
Infrared Signature and Folding Dynamics of a Helical B-PeptideGeronda Montalvo, Matthias M. Waegele, Scott Shandler, Feng Gai, William F. DeGrado J. Am. Chem. Soc./ DOI: 10.1021/ja100459aBiomedical, Protein AnalysisEC-QCL, Hedgehog, MIRcat2010
Chemical Imaging using Infrared Photo-thermal MicrospectroscopyRobert Furstenberg, Christopher A. Kendziora, Michael R. Papantonakis, Viet Nguyen, R. A. McGill Proc SPIE vol 8374: 837411-1/ DOI: 10.1117/12.919574Biomedical, Chemical ImagingEC-QCL, MIRcat2012
Mid-infrared microspectroscopic imaging with a quantum cascade laserKevin Yeh, Matthew Schulmerich, Rohit Bhargava Proc SPIE vol. 8726: 87260E-1/ DOI: 10.1117/12.2015984Biomedical, Chemical ImagingMIRcat, Hedgehog2013
Quantum cascade laser-based hyperspectral imaging of biological tissueNiels Krӧger, Alexander Egl, Maria Engel, Norbert Gretz, Katharina Haase, Iris Herpich, Bettina Kränzlin, Sabine Neudecker, Annemarie Pucci, Arthur Schӧnhals, Jochen Vogt, Wolfgang Petrich Journal of Biomedical Optics 19(11), 111607Biomedical, Tissue AnalysisEC-QCL, MHF2014
Breath Analysis with Broadly Tunable Quantum Cascade LasersKatharina Worle, Boris Miziakoff, Felicia Seichter, Andreas Wilk, Chris Armacost, Tim Day, Matthias Godejohann, Ulrich Wachter, Josef Vogt, Peter Radermacher Analytical Chemistry/ DOI: 10.1021/ac3030703Sensors, Analyzers & Spectrometers, PlasmaEC-QCL, Hedgehog2013
Concept and setup for intraoperative imaging of tumorous tissue via Attenuated Total Reflection spectroscopy with Quantum Cascade LasersFlorian B. Geiger, Martin Koerdel, Anton Schick, Axel Heimann, Kaspar Matiasek, Alois M. Herkommer Proc SPIE vol. 9412Biomedical, Cancer Research, Tissue AnalysisEC-QCL, Hedgehog, MIRcat2015
High-confidence, high-throughput screening with high-def IR microspectroscopyBenjamin Bird, Miles Weida, Jeremy Rowlette, Matthew Barre, David Arnone, Timothy Day BioOptics WorldBiomedicalSpero2014
Large scale imaging of tissue micro arrays (TMAs) using a tunable Quantum Cascade Laser (QCL) based microscopePaul Bassana, Miles J. Weida, Jeremy Rowlette, and Peter Gardner AnalystBiomedicalSpero2014
Quantum cascade laser-based mid-infrared spectrochemical imaging of tissues and biofluidsGraeme Clemens, Benjamin Bird, Miles Weida, Jeremy Rowlette, Matthew J. Baker Spectroscopy Europe/ DOI: 10.1039/C4AN00638KBiomedicalSpero2014
New Source Improves Infrared ImagingDaylight C & E NewsBiomedicalSpero2015
Vibrational Microscopectroscopy of Single ProteinsFujiyoshi, S. et. al. (Matsushita) J. Phys. Chem. LettBiomedical2010
Tunable external cavity quantum cascade laser for the simultaneous determination of glucose and lactate in aqueous phaseMarkus Brandstetter, Bernhard Lendl, Andreas Genner, Kresmir Anic Analyst/ DOI: 10.1039/c0an00532kBiomedicalEC-QCL, Hedgehog2010
Achieving Secondary Structural Resolution in Kinetic Measurements of Protein Folding: A Case Study of the Folding Mechanism of Trp-cageRobert M. Culik, Arnaldo L. Serrano, Michelle R. Bunagan, Feng Gai Chem. Int. Ed/ DOI: 10.1002/anie.201104085Biomedical, Protein AnalysisCW/ mode-hop-free, EC-QCL, Hedgehog, Pulsed Tunable Laser2011
New photoacoustic cell design for studying aqueous solutions and gelsJ. Kottmann, J. M. Rey, M. W. Sigrist Review of Scientific Instruments 82, 084903Biomedical, Chemical ImagingEC-QCL, MIRcat2011
In vitro measurements of physiological glucose concentrations in biological fluids using mid-infrared lightSabbir Liakat, Kevin A. Bors, Tzu-Yung Huang, Anna P. M. Michel, Eric Zanghi, Claire F. Gmachl Biomedical Optics Express/ Vol. 4, No. 7/ DOI: 10.1364/BOE.4.001083Biomedical, Glucose MonitoringHedgehog2013
In Vivo Noninvasive Monitoring of Glucosee Concentration in Human Epidermis by Mid-Infrared Pulsed Photoacoustic SpectroscopyM. A. Pleitez, O. Hertzberg, A. Bauer, M. Seeger, T. Lieblein, H. V. Lilienfeld-Toal, W. Mäntele Analytical Chemistry / DOI: 10.1021/ac302841fBiomedical, Chemical Imaging, Glucose MonitoringEC-QCL, Hedgehog2013
Photothermal deflectometry enhanced by total internal reflection enables non-invasive glucose monitoring in human epidermisM. A. Pleitez, O. Hertzberg, A. Bauer, M. Seeger, T. Lieblein, H. V. Lilienfeld-Toal, W. Mäntele Analyst DOI: 10.1039/c4an01185fBiomedical, Glucose MonitoringEC-QCL, Hedgehog2014
Measures for optimizing pulsed EC-QC laser spectroscopy of liquids and applications to multi-analyte blood analysisM. Brandstetter, C. Koch, A. Genner, B. Lendl Proc SPIE Vol 8993 DOI:10.1117/12.2038585BiomedicalEC-QCL2013
Quantum cascade laser-based hyperspectral imaging of bilogical tissueKroger, N., et. al. (Petrich) J. Bio OpticsBiomedical2014
Surface-enhanced mid-infrared spectroscopy using a quantum cascade laser,”Anton Hasenkampf, Niels Krӧger, Arthur Schӧnhals, Wolfgang Petrich, Annemarie Pucci Optics Express 5670/ DOI: 10.1364/OE.23.005670BiomedicalEC-QCL, Hedgehog2015
Submillisecond mixing in a continuous-flow, microfluidic mixer utilizing mid-infrared hyperspectral imaging detectionDrew P. Kise, Donny Magana, Michael J. Reddish, R. Brian Dyer Lab Chip/ DOI: 10.1039/c31c5117leBiomedical, MicrofluidsCW/ mode-hop-free, EC-QCL, Hedgehog2014
External-Cavity Quantum Cascade Laser Spectroscopy for Mid-IR Transission Measurements of Proteins in Aqueous SolutionMirta R. Alcaraz, Andreas Schwaighofer, Christian Kristament, Georg Ramer, Markus Brandstetter, Hector Goicoechea, Bernhard Lendl Anal Chem DOI:10.1021/acs/analchem.5b01738BiomedicalEC-QCL, Hedgehog2015
Infrared nanoscopy of Dirac Plasmons at the Graphene – SiO2 Interface,Zhe Fei, Gregory O. Andreev, Wenzhong Bao, Lingfeng M. Zhang, Alexander S. McLeod, Chen Wang, Margaret K. Stewart, Zeng Zhao, Gerardo Dominguez, Mark Thiemens, Michael M. Fogler, Michael J. Tauber, Antonio H. Catro-Neto, Chun Ning Lau, Fritz Keilmann, Dimitri N. Basov Nano Letters/ DOI: 10.1021/nl202362dNanoscaleHedgehog2011
Infrared absorption nano-spectroscopy using sample photoexpansion induced by tunable quantum cascade lasersFeng Lu, Mikhail Belkin Optic Express 19942, Vol. 19, No. 21NanoscaleHedgehog2011
Mid-infrared absorption microscopy with λ/100 spatial resolution using tunable quantum cascade lasersFeng Lu, Mikhail Belkin OSANanoscaleMIRcat2010
Near-field spectroscopy of silicon dioxide thin filmsL. M. Zhang, G. O. Andreev, Z. Fei, A. S. McLeod, G. Dominguez, M. Thiemens, A. H. Castro-Neto, D. N. Basov, M. M. Fogler Physical Review B / DOI: 10.1103/PhysRevB.85.075419NanoscaleMIRcat2012
Phase Controlled Homodyne Infrared Near-Field Microscopy and Spectroscopy Reveal Inhomogeneity within and among Individual Boron Nitride NanotubesXiaoji G. Xu, Gilbert C. Walker, Adrienne E. Tanur J Phys Chem A/ DOI: 10.1021/jp4008784NanoscaleEC-QCL, Hedgehog, Pulsed Tunable Laser2013
Tunable Phonon Polaritons in Atomically Thin van der Waals Crystals of Boron NitrideS. Dai, Z. Fei, Q. Ma, A. S. Rodin, M. Wagner, A. S. McLeod, M. K. Liu, W. Gannett, W. Regan, K. Watanabe, T. Taniguchi, M. Thiemens, G. Dominguez, A. H. Castro Neto, A. Zettl, F. Keilmann, P. Jarillo-Herrero, M. M. Fogler, D. N. Basov Science Mag/ Vol. 343NanoscaleMIRcat2014
Nano-Chemical Infrared Imaging of membrane Proteins in Lipid BilayersSamuel Berweger, Duc M. Nguyen, Eric A. Muller, Hans A. Bechtel, Thomas T. Perkins, Markus B. Raschke Journal of the American Chemical Society/ DOI: 10.1021/ja409815gNanoscaleEC-QCL, Hedgehog, Pulsed Tunable Laser2013
Vibrational nano-spectroscopic imaging correlating structure with intermolecular coupling and dynamicsBenjamin Pollard, Eric A. Muller, Karsten Hinrichs, Markus B. Raschke Nature Communications/ DOI:10.1038/natcomms4587NanoscaleMIRcat2014
One-dimensional surface phonon polaritons in boron nitride nanotubesXiaoji G. Xu, Behnood G. Ghamsari, Jian-Hua Jiang, Leonid Gilburd, Gregory O. Andreev, Chunyi Zhi, Yoshio Bando, Dmitri Golberg, Pierre Berini, Gilbert C. Walker Nature Communications/ DOI: 10.1038/natcomms5782NanoscaleEC-QCL, Hedgehog, Pulsed Tunable Laser2014
Structural analysis and mapping of individual protein complexes by infrared nanospectroscopyAmenabar, I., et. al. (Hillenbrand) Nat CommNanoscale2013
IR Near-Field Spectroscopy and Imaging of Single LixFePO4 MicrocrystalsI. T. Lucas, A. S. McLeod, J. S. Syzdek, D. S. Middlemiss, C. P. Grey, D. N. Basov, R. Kostecki Nano Letters/ DOI: 10.1021/nl5010898NanoscaleEC-QCL, Unicorn II2014
Method for Time-Resolved Monitoring of a Solid State Bilogical Film Using Photothermal Infrared Nanoscopy on the Example of Poly-L-lysineGeorg Ramer, Anna Balbekova, Andreas Schwaighofer, Bernhard Lendl Analytical Chemistry/ DOI: 10.1021/acs.analchem.5b00241NanoscaleEC-QCL, Hedgehog2015
Hyperbolic phonon-polaritons in boron nitride for near-field optical imaging and focusingPeining Li, Martin Lewin, Andrey V. Kretinin, Joshua D. Caldwell, Kostya S. Novoselov, Takashi Taniguchi, Kenji Watanabe, Fabian Gaussmann, Thomas Taubner Nature Communications/ DOI: 10.1038/ncomms8507NanoscaleEC-QCL, Hedgehog2015
Tip-enhanced infrared nanospectroscopy via molecular expansion force detectionFeng Lu, Mingzhou Jin, Mikhail A. Belkin Nature Photonics, DOI:10.1038/NPHOTON.2013.373NanoscaleHedgehog, Pulsed Tunable Laser2013
Tunneling Plasmonics in Bilayer GrapheneZ. Fei, E. G. Iwinski, G. X. Ni, L. M. Zhang, W. Bao, A. S. Rodin, Y. Lee, M. Wagner, M. K. Liu, S. Dai, M. D. Goldflam, M. Thiemens, F. Keilmann, C. N. Lau, A. H. Castro-Neto, M. M. Fogler, D. N. Basov Nano Lett. DOI: 10.1021/acs.nanolett.5b00912NanoscaleMIRcat2015
Characterization and control of a tunable quantum cascade laser beam parameters for stand-off spectroscopyFurstemberg, R., Kenziora, C. A., Papantonakis, M., Nguyen, V., McGill, R. A Proc. Of SPIE Vol. 9824 DOI 10.1117/12.2224003Standoff DetectionMIRcat2016
Low-threshold terahertz molecular laser optically pumped by a quantum cascade laserA. Pagies, G. Ducournau, J. F. Lampin Apl Photonics DOI 10.1063/1.4945355Standoff DetectionMIRcat2016
Infrared planar laser-induced fluorescence with a CW quantum-cascade laser for spatially resolved CO2 and gas propertiesGoldenstein, C. S., Miller, V. A, Hanson, R. K. Appl. Phys. B DOI 10.1007/s00340-015-6167-0Environmental MonitoringMHF2015
Reversible optical switching of highly confined phonon-polaritons with an ultrathin phase-change materialPeining Li, Xiaosheng Yang, Tobias W. W. Maß, Julian Hanss, Martin Lewin, Ann-Katrin U. Michel, Matthias Wutting, Thomas Taubner Nature Materials DOI: 10.1038/NMAT4649NanoscaleMIRcat2016
Imaging of Anomalous Internal Reflections of Hyperbolic Phonon-Polaritons in Hexagonal Boron NitrideAlexander J. Giles, Siyuan Dai, Orest J. Glembocki, Andrey V. Kretinin, Zhiyuan Sun, Chase T. Ellis, Joseph G. Tischler, Takashi Taniguchi, Kenji Watanabe, Michael M. Fogler, Kostya S. Novoselov, Dimitri N. Basov, Joshua D. Caldwell Nano Lett. DOI: 10.1021/acs.nanolett.6b01341NanoscaleMIRcat2016
Observation of a Luttinger-liquid plasmon in metallic single-walled carbon nanotubesZhiwen Shi, Xiaoping Hong, Hans A. Bechtel, Bo Zeng, Michael C. Martin, Kenji Watanabe, Takashi Taniguchi, Yuen-Ron Shen, Feng Wang Nature Photonics, DOI:10.1038/NPHOTON.2015.123NanoscaleMIRcat2015
Site-Specific Dynamics of β-Sheet Peptides and DPro-Gly Turns Probed by Laser-Excited Temperature-Jump Infrared SpectroscopyAlexander Popp, David Scheerer, Heng Chi,Tim othy A. Keiderling, Karin Hauser Chem Phys Chem DOI: 10.1002/cphc.201501089Biomedical, Time ResolveHedgehog2016
Infrared spectroscopic imaging detects chemical modifications in liver fibrosis due to diabetes and diseaseHari Sreedhar, Vishal K. Varma, Francesca V. Gambacorta, Grace Guzman, Michael J. Walsh Biomedical Optics Express DOI: 10.1364/BOE 7.002419BiomedicalSpero2016
Standoff photoacoustic spectroscopyC. W. Van Neste, L. R. Senesac, T. Thundat Applied Physics Letters 92, 234102Standoff DetectionEC-QCL, Hedgehog2008